Sherlock…handles things in his own way.
The circumstances in Hounds of Baskerville were a little different than in BC. When Sherlock has his big freak-out, he’s been drugged and is much more high-strung than he normally would be. Though, that’s not to say that he handles that topic perfectly.
Sherlock’s entire reality is built on science and logic, what he can see and feel and prove. He’d refuse to believe in the supernatural unless it was right in front of him. He can’t exactly deny the existence of the bitty bros, but he will struggle with the idea of witches and a curse. We’ll just have to wait and see if he runs into ghosts and vampires to gauge his reaction.
Brothers Apart 