BA Canon: Yes
Timeline: After The Golden Touch
Sam groaned, doubling over. His bottlecap shifted far enough on the pillow to tip, spilling the Coke all over the plush white surface. It spread out a dark stain.
Dean poked his head out of the bathroom, concern on his face at the quiet moaning. “Sam, is everything…”
He spotted the doubled-over form on the pillow. “Sam!” Dean was over at the bed in an instant.
Sam felt himself fall onto his back, thrown off balance from the sight of Dean growing so large, so fast. He blinked up at his older brother looming overhead for a few seconds before curling up again in pain.
It was so all-encompassing he didn’t even pay any mind to the two hands that cupped carefully around him, slowly edging under his body. Sam was lifted up into the air, finding himself level with concerned green eyes.
A finger brushed against his arms, trying to coax him out of his crumpled position. “Sam, did you drink the soda?”
“Uhhh… maybe. W…why?”
Dean’s eyes crinkled at the corners, and he moved his hand so Sam could lay flat. “I think maybe next time we should wait for it to go flat.”
Sam buried his face in the thick, soft skin underneath. He felt a burp come up, lessening the pressure in his middle.
“I think maybe you’re right.”